Toprol XL
Last Edited: April 16th, 2012

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Toprol XL, also known as metoprolol succinate, is a a drug developed to treat high blood pressure, also called hypertension. It in a group of medications called beta-blockers. Beta-blockers lower the heart rate and allow increased blood circulation through the heart, veins, and arteries.

Toprol may also be used to treat angina (chest pain) or to treat or prevent heart attack. It may also be administered by a physician for other purposes.

Important Information

Do not take Toprol XL if you are allergic to metoprolol. It should not be used if you have serious heart problems such as a heart block, sick sinus syndrome, or a slow heart rate. Inform your physician if you have congestive heart failure, low blood pressure, circulation issues, pheochromocytoma, asthma, diabetes, depression, liver or kidney disease, thyroid disease, or severe allergies.

Toprol XL may cause a delay in your reaction time. Driving or other potentially hazardous activities should be done with caution. Alcohol may increase side effects of this medication.

It is important to take medication as prescribed. Do not stop this medication without your physician's knowledge, as a sudden stop may increase symptoms of your condition. Inform all doctors participating in your care that you are taking Toprol XL. You may not have symptoms with high blood pressure, so it is very important to continue your medication even if you feel well.

Toprol XL is often used in conjunction with diet, exercise, and other medications. Follow your physician's recommendations carefully.

Before Using Toprol XL

Inform your physician of any of the above allergies or any serious health issue you have. Toprol is an FDA category C medication. It is not known if the medication will cross the placenta and harm and unborn baby. The medication does pass into breast milk and may harm a breastfeeding baby. It should not be used while breastfeeding.

Some medications may interact with Toprol XL. Inform your doctor if you are taking any of the following:

  • Digoxin (digitalis, Lanoxin)
  • Clonidine (Catapres)
  • Ritonavir (Norvir)
  • Terbinafine (Lamisil)
  • Diuretics (Lasix, Bumex, ect.)
  • Cold medications, stimulants, or diet pills
  • Chloroquine (Aralen) or hydroxychloroquine (Plaquenil, Quineprox)
  • Antidepressents or medications for mental illnesses, including bupropion (Wellburtin, Zyban), fluoxetine (Prozac, Sarafem), paroxetine (Paxil), Thioridazine (Mellaril), ect.
  • MAO inhibitors, including furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate)
  • Heart medications, including nifedipine (Procardia, Adalat), quinidine (Quin-G), propafenone (Rythmol), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem)
  • Athhma or breathing medications, including albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair).

Other medications may interact with Toprol XL, so be sure that your physician has a complete list of your current medications.

How is Toprol XL Used?

This medication works directly on the heart and blood vessels. It must be taken exactly as prescribed by your physician. It is best to take Toprol XL with food to avoid stomach upset. It may be crushed or divided if your physician approves. Missing doses may make your current condition worse, so take at the same time every day.

Keep all scheduled appointments with your physician to monitor your blood pressure. Follow all diet and exercise recommendations made by your doctor.

Side Effects

Although uncovmmon, a severe allergic reaction is possible. Get immediate emergency medical attention if you have any of the following symptoms:

  • Hives
  • Difficulty breathing
  • Swelling of face, lips, tongue, or throat

Serious side effects should be reported to your doctor immediately and include:

  • Chest pain, pounding heartbeats, or fluttering in the chest
  • Dizziness, fainting
  • Shortness of breath
  • Swelling of hands or feet
  • Nausea, abdominal pain, decreased appetite, dark urine, or clay-colored stools
  • Yellowing of the eyes or skin
  • Increased bruising or blood from the nose, mouth, vagina, or rectum
  • Depression, confusion, or cognitive difficulties
  • Decreased circulation, including cold hands and feet

Minor side effects are more common. Report to your physician if they become chronic or bothersome:

  • Dry mouth, constipation, heartburn, vomiting, or diarrhea
  • Lowered libido or sexual difficulties
  • Headache, drowsiness, or lethargy
  • Sleep difficulties
  • Anxiety or nervousness