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AMITIZA (24 mcg) twice daily is approved to treat Chronic Idiopathic Constipation in adults. "Idiopathic" means the cause of the constipation is unknown and not due to an underlying illness or medication.

Amitiza is a chloride channel activator. It increases fluid secretion in your intestines which increases intestinal muscle movement and helps make it easier to pass stools (bowel movements).

Amitiza is used to treat chronic constipation in adults. It is also used to treat irritable bowel syndrome in women with constipation as the main symptom.